An exanguination of a Greenwich, Connecticut, man leads Mulder to believe that aliens performed the task. Scully and he talk to the man's little girl, who gives them an unusual account. At the same time, a similar exanguination in San Francisco turns up another young girl who looks exactly like the girl in Greenwich.

Bishop returns from the future to again attempt to fix his world, this time trying to stop a plague from infecting mutants. But his noble actions lead to a far greater tragedy.

It's an emotional farewell for the pregnant Duffy as she leaves Charlie and the rest of the staff at Holby to become a full time mother. She finds herself counselling the distraught mother of a cot-death baby, as Ash and Adele are both keen to step into her shoes. Jane turns detective and discovers a stab victim is an illegal immigrate A gypsy makes plans when he's told he's got TB and not Aids. As Charlie and Duffy make up, Mike Barrett returns.