When a master painting instructor is pushed off a cliff, Mark and Rex scope out the art world to get to the bottom of a picture-perfect murder.

In the aftermath of Faith's deepening entanglement with Malcolm, her undercover work and emotions collide. Meanwhile, Amanda faces an unexpected challenge as Seth and Angie's next chapter begins to take shape.

Jack has a date with the noose. Will Belle and Fagin be able to help our hero dodge his fate?

On the eve of Port Wenn's annual blueberry festival, Martin treats a local man who has apparently become blue from eating too many blueberries. Also, Martin is disturbed by Aunt Sarah's lack of attention to her health, Mark faces the repercussions when his vision issues may stem from his sexual history and Louisa is determined to win the pie competition.

While navigating the fallout from Katie's secret, Amy treats a critically ill patient with a dark one of her own. Gina and Jake evaluate a world-class poker player. Sonya and TJ investigate their theory behind Joan's frequent absences and Richard returns with a trick up his sleeve.

As trade wars cripple the liquor market, Appalachia's moonshiners invent new ways to meet demand for tax-free booze. And when Canada calls for tariff-free liquor, even legal distillers return to the outlaw side in a cross-border bootlegging operation.

Jordan Klepper reviews new details from the unredacted Epstein files, noting extensive references to Trump and examining the broader fallout. He covers public backlash toward King Charles, questions faced by Commerce Secretary Howard Lutnick regarding visits to Epstein Island, and scrutiny of paleontologist Jack Horner's associations with Epstein. Klepper also highlights RFK Jr'.s past field trip with Epstein and Ghislaine Maxwell. In a new Sports War segment, Klepper and Desi Lydic debate major sports headlines, including Bad Bunny's historic Super Bowl halftime show, a Winter Olympian's protest against ICE, and a figure skater competing in a Minion costume. Actor and filmmaker Tim Blake Nelson joins to discuss his novel Superhero, exploring how his experience on film sets shaped the story, the cultural role of superhero films, and how these narratives reflect America's polarized views of good and evil.

A game-changing charge ups the stakes, forcing Mickey to make his toughest decision yet. Surveillance footage gives Izzy a new angle on the case.

Relationships are tested at Bree's photography exhibition. Lucy devises a plan to finally put rumors to rest.

A lost suitcase causes even more stress for the gang. Victor's father puts Rosa to the test and Ez?chiel takes something very precious from Marionnaud.

Samira uses the disappearance of a neighbor's dog as a ruse to convince her new friends to break into the Victorian so she can confirm her suspicions about Gary; once inside, the group is shocked to find far more than they were looking for.

Unable to let go, Koleev descends upon the safe house with everything he's got. Meret and Simon will have to trust each other in order to survive.

When the Dionisi siblings inherit the family racing team, Elena goes rogue and starts her own squad to beat her brother in the Italian Gran Turismo.

As Debbie considers coming clean, the blackmailer decides enough is enough. But this endgame puts Harry and William in genuine danger - is it all over for the Fendons?