Sabrina wants to spend her birthday with her boyfriend, Josh, but her Aunt Irma comes to visit from the Other Realm and puts Harvey on trial because he knows Sabrina is a witch and is determined to test him to see where his loyalties lie. Meanwhile, Roxie's ex-boyfriend Isaac Hanson, playing himself, surprises her by performing with his brothers Taylor and Zac, at the soup kitchen where she volunteers.

When Asha's militant group comes under fire, Max figures that it's all because of a Manticore-engineered military strategist, another transgenic called Brain. Brain sets out to protect Max as best he can, after he's called upon to discover who really betrayed the group.

A 6-year-old boy wounded in a shooting is brought to the hospital ER but abandoned by the brother who reported it and their mother. The case leads the detectives to a woman who is on the run from her abusive lover, a drug dealer whom she saw kill a rival.

Chloe and Tony feel the presence of the police as they interview Lewis' escape, convinced someone inside the department helped as Max faces the disciplinary hearing.