Sutton visits her hometown, but falls into a familiar pattern while there. Jane finds a big story, but it could have serious ramifications for Jacqueline. Kat is reluctant to share her new romance with Jane and Sutton.

After some of the participants are raided by predators, they scramble to protect their hard-won food. Winter moves in, bringing with it new opportunities for those who are prepared, and new threats for those who aren't.

Trevor covers international COVID-19 news, Dr. Michele Harper discusses her memoir "The Beauty in Breaking", and Patton Oswalt talks about "I'll Be Gone in the Dark".

Conan welcomes Emily Mortimer.

Jimmy welcomes jim Carrey, Jenny Slate, and a musical performance by Luke Combs.

Stephen welcomes an interview with and musical performance by The Chicks.

As Niles and Cliff set out to find a missing Dorothy, Larry is tasked with handling Niles' old research team when the ageless aeronauts return from space.

Bernard Marx is preoccupied with recent events in New London as he and Lenina Crowne take a trip together; John struggles with a dilemma.