Calvin receives an unexpected honor that sparks mixed emotions, while Malcolm's ghostwriting gig takes a wild turn after a viral outburst from his celebrity client.
When a robbery at a community clinic turns deadly, the team investigates a drug trafficking crew and soon uncovers that the clinic's doctor may be more involved than they initially thought. Meanwhile, Isobel and her stepdaughter are at odds over a family issue.
Watson and the fellows race against time to save the life of Xavier, a 21-year-old athlete with a fast-growing, seemingly incurable cancer. Meanwhile, Mycroft Holmes lets Watson know his team's work at UHOP may no longer have funding available.
Greg Davies hosts the comedy quiz as Nadine Coyle, Tom Grennan and Chris McCausland join team captains Noel Fielding and Sophie Willan and regular Jamali Maddix.
Elvira uncovers Walter Eustace as the screwdriver killer's hirer, kills Hughie to protect Ward's memory, and manipulates Vivienne to secure her future. She leaves Emerson, starting anew in London.