The four remaining teams take off from Lion's Rock in Sri Lanka and learn that they must fly to Shanghai, China. The teams catch the same flights via Hong Kong and then through to Shanghai which arrives later that night.
The teams face communication difficulties while trying to grab taxis to get to Yu Yuan Gardens.
The teams eventually arrive and discover that they must wait until the next morning for it to open.
The teams are then instructed to make their way by taxi to Huaneng Union Tower where one team decides to use the third and final Yield on another.
Next, a Roadblock has team members lowering down a building while making sure to locate a hidden message printed half way down and then teams must use this to reveal to a man at the bottom to get their next clue.
Next, the teams travel by taxis to the Monument of the People's Heroes on Shanghai's most popular mile, the Bund. There, teams must search through a group of Tai Chi performers for the one with their next clue.
Teams then make their way to the docks of Shanghai where they encounter a Detour. One involves "Bricks," a more physical task, while other as "Ice" which requires transporting ice and then breaking it into small parts. No one chose to do "Ice."
The teams then rush to get to the next Pit Stop, the Peace Hotel South.
In the end, one team is only just late by a few minutes and arrives last.
Although fearing the worst, they are not eliminated, as this is the last of three pre-determined non-elimination legs.
However, Phil tell us someone will fall victim to the final elimination on the next leg.
Rory is bummed when Logan, whom she helped write an article for the Yale Daily, doesn't return the favor by inviting her to be his date at a book signing party thrown by his father. When Richard sees Emily talking to man she dated, he rear-ends her car, forcing her to ride home with him. The Gilmores reconcile and decide to renew their wedding vows. Emily warns Christopher that Lorelai and Luke are getting serious and he had better do something quickly if he hopes to end up with Lorelai.
Legendary jazz musician John Henry Giles is checked into the hospital and when he's told he's dying from ALS, he signs a DNR to avoid a slow death. House disagrees with the diagnosis and goes against everyone's wishes when he violates the DNR to save Giles' life. The decision lands House in court, drives Foreman to consider taking another job, and results in Giles' paralysis worsening. But when the patient inexplicably starts getting better, the team has to figure out the mystery in reverse and find out why his condition is improving. Meanwhile, Dr. Foreman meets with an old friend who offers him a West Coast partnership.
Nathan comes clean with Haley about his past relationship with Taylor, although Haley continues to email Chris without telling Nathan and Taylor finds out. Lucas and Karen remain at odds over his refusal to take the HCM test. Keith proposes to Jules. Meanwhile, Brooke fights for better working conditions at her new job. Lucas decides to take the HCM test.