Stardate: 43125.8 Wesley loses a couple of the nanites that he was studying, which then multiply and evolve, finally reaching a collective intelligence. When they start feeding off of Enterprise's computer chips, several systems failures begin to occur, and this delays a very important scientific mission. The visiting scientist, there to oversee this important scientific mission, then tries to destroy the nanities, to save his once in a life time spatial observation. Now the crew must fight the nanites attempts to take over the ship, and their attempts to seek revenge on the visiting scientist.
MacGyver and an old friend dash around the world searching for the artifacts necessary to locate the Holy Grail, just one step ahead of a ruthless man on the same trail.
The network sends Jim to Libya for two weeks, so they can audition a handsome new anchor for FYI; they don't count on the retaliation of Murphy and the gang.