SG-1 travels on the Earth ship Odyssey to Atlantis to both try to dial in the 'super gate' nearby, and to let Daniel continue his search for the anti-Ori weapon while staying at Atlantis. Things get tense as an Ori ship approaches Teal'c's position at the super gate, just as a Wraith hive ship approaches the Odyssey's position in the Pegasus galaxy, where they are trying to activate a gate connection to the super gate back in the Milky Way.
A man from another world has an unusual effect on the Atlantis team, causing them to behave strangely. The few unaffected team members must uncover the cause.
As the Whiskers family is finally recovering from the split, more problems are created when Daisy gives birth to her pups in the wrong burrow and she needs help. Youssarian goes to her rescue.
Nathan embarks on a hunt to find out who failed to dispose of the needle that pricked him. A patient in the hepatitis B clinic tries to steal drugs, jeopardising Maggie's attempt to keep it open, while Nina and Kelsey make a bet on whether Greg is gay after discovering he wears mascara.