Elaine comes across a cartoon in the New Yorker, but can't figure out why it's funny. She then becomes determined to get her comic published. Kramer's honesty gets Jerry in trouble with Sally, an old friend of Elaine's, and she begins to do stand-up about how mean Jerry is. George's new girlfriend looks like Jerry, but he refuses to believe it.
Carter faces a dilemma during a blood shortage when a serial rapist is in need of a transfusion. Carol and Weaver deliver the baby of a mentally challenged couple who fear a relative is going to take the child away. Benton turns down Corday's romantic offer. Weaver actively campaigns against Synergix. Doug comes to grips with his relationship with Carol and tells her that he'll wait for as long as she needs. Cynthia pours her heart out about her relationship with Mark to an uninterested Doug.