When gang-related gunplay goes down in an emergency room, Horatio and the team must find the gang members responsible. The evidence suggests that an orderly in the hospital recognized the wounded gang member, who possibly killed one of the orderly's friends and alerted gang members to his location. However, the evidence doesn't match up and the CSIs discover that a cheating girlfriend, not gang retaliation, may be behind the shooting. Meanwhile, Ryan questions a mother in the emergency room after her story regarding her child doesn't add up.
After Ed is kidnapped, Danny and Mike must mount a search of the city to locate him. They receive instructions on how to pay the ransom and they follow through only to be double-crossed. Sam holds a Vegas style wedding for one of her clients and Delinda arranges for the Montecito to host Duran Duran.
Allison keeps having dreams that her husband Joe is determined to disprove. In a drastic measure he submits her dreams to different law enforcement agencies. Much to his surprise he gets a hit on a case out of Texas, involving the murder of a teenage boy.
Frank's estranged fathwe Neville visits Chatsworth to meet his new grandchildren. Whilst the rest of the family welcome him with open arms, Frank finds his life turned upside down, as he is forced to relive painful memories from his childhood. Meanwhile, Karen Jackson returns to Chatsworth and gets a job at the Jockey by convincing Jez that she is a lesbian. Veronica is riled when Karen becomes flirtatious towards Kev, and a feud between the two women begins.
