Simon considers dating a 16-year-old pregnant girl named Sally who he meets on the bus. Although, there is more to Sally's past than what she is letting on. Meanwhile, Annie decides to accept Robbie's offer in renting the room over the Camden's garage that both Lucy and Matt were hoping to get. Also, a carpenter pretends to fake an injury while working on the Camden's garage and tries to sue them. Lastly, Mary gets more serious with being a firefighter, mother and wife to Wilson and Billy.
John is more irritable than usual when he tries to quit smoking; Reggie believes a friendly customer stole all of her good luck and left her with his bad fortune.
Gunn is put to the ultimate test while Angel Investigations are investigating recent demon slaughters that just happen to be harmless ones. He soon discovers that his old gang is the ones responsible for these deadly spring of killings. They soon have Gunn confronted for his alliance with a vampire. How will Gunn handle this situation?
Jordan is assigned to a mystery woman after a torso is found, which is quickly assigned to the prison system. Jordan struggles in finding out who the woman is and who murdered the victim.
As Doug is about to break what was once thought of as an unbeatable record, the tension between he and the guys at IPS mounts. For 18 years, Iggy Stenkowski's record of 951 consecutive perfect delivery days has remained intact, and the guys resent Doug as he's about to beat it and replace the legendary Iggy's plaque with one of his own.
Anton Meyer is seriously injured in a road-rage incident and is brought to Holby for an emergency operation. Mike Barratt's replacement Ric Griffin arrives. Alex Adams plays detective when he realises that the wife of an apparent road injury victim admitted at the same time is driving around in Meyer's car.