Blair is over the moon that she is dating royalty and has every intention of becoming a royal herself, but a scheming Chuck has other plans for Blair and her new love, Marcus, when he introduces Blair to Marcus' stepmother who happens to be Catherine. Meanwhile, Nate learns the downside to having an affair with Catherine when he keeps getting caught in his lies and learns his family has gone bankrupt due to his father jumping bail.

After the Jeep explosion, John's 16th birthday makes him confront the fact that he's destined to be alone. Meanwhile, after Cromartie's massacre, Agent Ellison must face off against both the Feds and his faith.

An FBI informant is the prime suspect in the deaths of two Tijuana police officers; Pope, Taylor and Brenda must deal with a public relations mess when a newspaper prints an unflattering story about Priority Homicide.

Tree Hill residents are surprised to learn that Luke and Peyton have decided to tie the knot. Brooke tries to adjust to life after the robbery at "Clothes Over Bros". Nathan and Haley receive devastating news and Nanny Carrie's return creates more blanks than answers, after she kidnaps Dan - whose life hangs in the balance.

Michael and the team have one day to find the next cardholder or they risk going back to prison. Mahone seeks revenge on Wyatt who is attempting to extract info on Sara's whereabouts, while T-Bag finds the gateway to his new identity and future.

Nancy talks to the DEA and tries to figure a way out of her situation.

Brody is still in jail, so the girls try to come up with a way to get him out. Plus Audrina and Lauren finally sit down and talk to each other.

Jerry defends a man accused of murder but the only eyewitness is in Guatemala. Michelle has the chance of trying her first murder trial and tries to remember to be a good lawyer in the process. Meanwhile, Richard defends a man accused of assault and Charlie runs into a former lover in the courtroom.

Rachel's growing alcohol dependence sends her family over the edge. Her careless actions could spell the end for one of them.

Lawson and Grace try to talk-down a troubled teenager when she threatens suicide, trapped on a rooftop with her young boyfriend. She was later found to have killed her boyfriend's father. Grace's inexperience is quickly revealed when she tries to fix the situation, which ends in the young woman's tragic death.

Jac discovers a big secret whilst looking for dirt on Faye. Jayne finds herself in serious trouble when she has to face the board. Connie might be the only person able to save the day.

Don gets a new job working for Karl's dad, Glen. While there, the feud between the two increases and Don finds the father figure he never had.