The race for Chief resident intensifies as Joan tasks Amy and Sonya with evaluating each other's case work. Amy tends to a politician with a disability whose dire health complications threaten to interrupt a crucial vote. Sonya struggles to find a solution to her combative patient's excruciating abdominal pain. Michael's parents come to town causing more family drama for him and Katie.
Dr. Amy Larsen must navigate an unfamiliar world after a brain injury erases the last eight years of her life. She can rely only on her estranged 17-year-old daughter, whom she remembers as a 9-year-old, and a handful of devoted friends, as she struggles to continue practicing medicine, despite having lost nearly a decade of knowledge and experience.