As Senator Collins pushes to make a public statement and announce a reward for any tips regarding the inexplicable disappearance of his wife, FBI Agents Kelton and Mei pursue leads that uncover elements that expand the scope of the investigation. Peter Manning, the man from Sara's past, remains determined to provide authorities with everything he knows, while the senator's ex-wife, Jessica Nevins, seeks to reconnect with their kids during this tragic and trying time.

The Petersons, Kyle's real parents, arrive to take him home, but Kyle is skeptical about his biological ties, so he turns to Tom Foss for answers. Meanwhile, Stephen has trouble accepting that Kyle may be leaving.

Once again, the PHD finds themselves wading through suspects in the murder of the star witness in a capital punishment case.

When Estelle, Pope's angry ex-wife, spills the beans about Brenda to her team, Fritz begins to wonder how she really feels.

Alex alienates Scott's best friends from Montana with her overly competitive spirit; Stephen is offered a partnership with another law firm, but Bill tries to keep him from leaving.

Mahone tries to lure the escapees by targeting an imprisoned LJ. Michael and Lincoln come up with a plan to free LJ from jail. Sucre, Abruzzi and C-Note have a plan of their own, but only to break free of their pursuers.Meanwhile, Bellick and Warden Pope feel the heat following their unsuccessful attempts to capture the escapees.Tweener infiltrates a bunch of college students on their way to spring break.

The OCC crew decide to mass produce a bike for the public.

Its career day at school, and Sophie decided to follow Gene around for the day. Shannon is furious to learn that Gene took 13 year old Sophie to the filming of a sexy exercise video.

Alex accidentally gets Scott kicked out of his apartment while he's in Montana visiting friends, and she fears that Scott will move in with her.

While Nancy is trying to figure out what do with Peter, she comes home to problems of plumbing that are related to Shane and his arrival into puberty. Celia enrolls Isabelle in boot camp and ends up getting sucked into it herself. Heylia is interested in a Nation of Islam member and his bean pies.

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