Rhade, Harper, and Beka each have some dealings with the "Stranger", he is shortly murdered. Now they're all on trial for his death. The guilty party will be killed at the end of the trial, but there's more to this trial than they suspect.
Despite everyone's protests, Joan allows her snobby, Ivy League-educated guidance counselor to advise her against applying to college. However, after Joan relays her plans to Roger, an engaging college student on the campus she's visiting, he tells her that college is attainable and persuades her to hire him as a tutor. Meanwhile, Adam becomes jealous of Joan's rapport with Roger; Will sees a dark side of Lucy; Helen questions her commitment to Catholicism, and Beth finds it difficult to resume a relationship with the wheelchair-bound Kevin.
Cate is shocked to discover that Principal Gibb (Adam Arkin, ''Chicago Hope'') has hired C.J. to be a substitute teacher at the high school. But when C.J. catches Rory cheating on a test, he is torn about reporting it when Cate tries to persuade him to look the other way. Meanwhile, when Bridget breaks her leg because of Kerry's blunder, she makes her little sister's life a living nightmare.
While Cate finds herself becoming jealous of Principal Ed Gibb's (Adam Arkin, ''Chicago Hope'') new girlfriend, Cheryl (Pamela Anderson), C.J. is asked by Ed to help tutor Cheryl for her G.E.D.s -- and finds himself unwittingly being hit on by her. Meanwhile, Rory feels awkward after Cate accidentally interrupts him during a private moment.
Ellen starts to panic when she finds out her fathers coming to visit and ends up missing her immigration meeting. McFly pop by Holby A&E to surprise two fans who went a long way to meet the famous pop band. Comfort is furious to find Sam tampering with her marriage certificate leading to an argument between Tess and Comfort.